Author ' s response to reviews Title : Patients with migraine with aura have increased flow mediated dilation
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Patients with migraine with aura have increased flow mediated dilation
BACKGROUND Endothelium-derived nitric oxide (NO) mediates the arterial dilation following a flow increase (i.e. flow-mediated dilation, FMD), easily assessed in the brachial artery. NO is also involved in cerebral hemodynamics and it is supposed to trigger vascular changes occurring during migraine. This study aimed at investigating whether migraine patients present an altered response to NO al...
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Change the first sentence of the Background as follows: “Migraine has been associated with an increased risk of cardio and cerebrovascular diseases”. Response: We believe that the term “cardiovascular” covers all types of vascular disorders, including cerebrovascular disorders, and is widely used as such in the medical literature. Introduction The sentence regarding the association between migr...
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Abstract Background: Dysfunction of the autonomic nervous system has long been a subject of considerable debate and a large number of studies have disclosed contradictory results. The aim of this study was to compare cerebral vasomotor reactivity in migraine with aura (MWA) patients with migraine without aura (MWO) ones. Methods: Ten MWA patients (7 females and 3 males mean age: 39.70 years, S...
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Background: Visual evoked potential (VEP) is regarded as a useful, reliable and non-invasive technique for the diagnosis of lesions in the optic pathway. This technique was used to investigate visual function in migraine. Materials and Methods: 53 migraine patients (27 migraine cases with aura and 26 common migraine cases) and 55 controls were prospectively enrolled in this study. Visual ev...
متن کاملTranscranial doppler sonography diagnostic value for the cerebral flow velocity changes in the interictal phase of classic migraine
Background: An imbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the pathophysiology of migraine. The purpose of this study was to determine the transcranial doppler sonography (TDS) diagnostic value for the cerebral flow velocity changes in the interictal phase of classic migraine. Methods: This study was carried out on 46 pa...
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